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Focal hyperpigmentation: Dark patches on the skin, including on the gums, may occur
ROS activate the MAPK pathway by modulating redox-sensitive kinases and phosphatases
Metcalfe-Roach A, Yu AC, Golz E, Cirstea M, Sundvick K, Kliger D, et al
6 Discussion 6.1 Principal findings: Evidence stratification and core conclusions Based on systematic database retrieval, this review establishes an evidence base guided by the correlation to causality grading framework, which is used to integrate the stratification and mechanism of research on traditional Chinese medicine/natural products, rheumatoid arthritis (RA) and intestinal microorganisms from 2015 to 2025
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