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Symptoms of anemia include: fatigue weakness dizziness difficulty concentrating Iron deficiency anemia is the most common form of anemia in the United States

N Engl J Med 352:16851695 Ridker PM (2016) From C-reactive protein to interleukin-6 to interleukin-1: moving upstream to identify novel targets for atheroprotection

The MOTS-c side effects profile is relatively mild, though the peptide faces bioavailability and stability challenges that limit its clinical development