This type of reaction is not typically encountered in conventional rodent toxicity studies
L-theanine supports relaxation and mood by increasing alpha-wave activity, and levels of serotonin, dopamine, and GABA in the brain.* L-theanine also has been shown to block binding of L-glutamic acid to excitatory glutamate receptors in the brain.* Glutamate receptor subtypes have been shown to modulate excitability associated with anxiety, while in depression, a hyperfunctioning glutaminergic system also may be an issue.* Continuous administration of L-theanine has been shown to increase expression of brain-derived neurotrophic factor (BDNF) protein, a protein which plays a role in neural plasticity and neurogenesis.* *These statements have not been evaluated by the Food and Drug Administration
Here, the consumption of BP led to the greatest increase in ex vivo proliferation of lymphocytes, while these results could simply be related to the presence of a great concentration of vitamins, trace elements, and amino acids that stimulate differentiation and proliferation of immune cells (161, 163)
Managing this itch is a critical first step in any effective treatment plan
