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Considering the mechanistic overlap in the development and progression of CKD in type 1 and type 2 diabetes, there exists a strong rationale for simultaneously developing novel CKD therapies for use in both type 1 diabetes and type 2 diabetes and studying the repurposing of existing type 2 diabetes CKD therapies for the treatment of CKD in people with type 1 diabetes

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Paradoxically, intragastric gavage of BTR agonists in mice was associated with only a transient increase in food intake during the first 30 min, followed by a sustained suppression of intake over the subsequent 4 h (55)