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Goniewicz, associate professor of oncology at Roswell Park Comprehensive Cancer Center told Newsweek that e-cigarettes "contain nicotine and emit particulates and several toxicants that may negatively affect heart and blood vessels of users." He said the cholesterol study shows those who use e-cigarettes and combustibles had "no improvement in health outcomes." "If [a] smoker seriously considers e-cigarette as a substitute product for combustible cigarettes, he or she should switch completely," he said