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According to the US National Heart, Lung and Blood Institute, this sign is diarrhoea

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This kind of "mopping up" activity can be beneficial for those dealing with headaches and/or migraines, inflammation, cold hands and feet, sore muscles and joints, fatigue, lack of motivation, memory challenges, feeling lightheaded when standing, brain fog, as well as symptoms of Chronic Fatigue and/or Fibromyalgia

meaning that animal studies have shown some adverse effect or there are no well-controlled studies in humans, but potential benefits may warrant use despite potential risks