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however, no substantial progress has been made in clinical practice

The U.S., which is among the key markets of GLP-1 drugs biosimilars, has benefited from rising expenditure on healthcare as well as the need for advanced treatments for metabolic diseases

The candidates that exist in 2026 are: clinician judgment (the gold standard, but in short supply), expanded laboratory work (DEXA for body composition, CGM for glycemic patterns, metabolic panels of increasing sophistication), patient-reported priorities (the founder who tells you he cares about muscle is providing useful prior information), and, increasingly, genetics

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