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Consequently, it is harder to reverse addiction originating in this stage compared with later in life." [96] Adolescents are particularly susceptible to nicotine addiction: the majority (90%) of smokers start before the age of 18, a fact that has been utilized by tobacco companies for decades in their teen-targeted advertising, marketing and even product design

It is also produced when a pipe, a cigar, an electronic cigarette or marijuana is smoked

E., Bullen, C., Krishnan-Sarin, S., Rigotti, N