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Trulicity vs Ozempic: Comparing Their Similarities and Differences While Trulicity and Ozempic are prescription drugs belonging to a group of medications known as GLP-1 receptor agonists used to treat type 2 diabetes that can reduce the risk of major cardiovascular events in adults with this conduction who have existing heart disease or risk factors, they have a number of differences

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Research consistently shows that GLP-1 users lose significant lean muscle mass alongside fat, with some studies reporting that 20-40% of total weight lost is lean tissue