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(6) Meta-analyses: A systematic review & meta-analysis found that in autistic children with cerebral folate deficiency or folate receptor alpha autoantibodies, treatment with folinic acid (leucovorin) was associated with improvements in communication, irritability, and other core symptoms

Hu H, Ding J, Zhang S, Li Y, Bai L, Yuan N

In fact, new studies have shown that the inhibition of renal glucose reabsorption reduces blood pressure, ameliorates glucotoxicity, favors weight loss, and induces hemodynamic effects that lead to improved cardiovascular and renal outcomes in T2DM (50, 51)

Photoprotective carotenoids, particularly zeaxanthin and lutein, protect cells against UV insult