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Description

Process refinement occurs before process transformation can

To account for patient variation, patient effects and patient-by-time interaction were included as random (from a bivariate normal distributed with mean zero and an unstructured covariance matrix)

In persons 70 years old, vaccine efficacy was 85.1% in the fourth year after vaccination.12 Immunogenicity data suggest that the protective effect of Shingrix will persist for at least 9 years after vaccination.13 The efficacy of Shingrix in persons who receive only one dose is not known