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The fine particulate matter (PM2.5) present in smoke, along with the chemical irritants released during combustion, can stimulate inflammation and irritation in the respiratory system

Researchers have identified the SV40 virus as a potential risk factor, but more research needs to be done on this topic before anything conclusive can be said

He noted that federal efforts have usually been a lot weaker than those of states and municipalities on this issue and pointed to the FDA's report last year, which included the "lost pleasure" of smoking as a "cost" in a cost-benefit analysis of the proposed graphic warning labels

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