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Studies reporting a significant association: summary and critical appraisal Despite the studies above being reassuring in lacking statistically significant evidence of respiratory outcomes of EC use by both youth and adults who never smoked, other studies have reported mixed outcomes indicating possible respiratory risks following EC use

Facing nicotine withdrawal The physical symptoms of nicotine withdrawal start within an hour of quitting, and may be at their worst in two or three days

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One of the biggest concerns for people when it comes to substances like nicotine and vaping is whether it will lead to weight gain or weight loss