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Avoid makeup or skincare products near the treated area for at least 24 hours to minimize irritation and potential contamination

Ensure that at least 48 hours have passed before you prepare your new dose

At the signaling level, the cascade initiated by ipamorelin binding to GHS-R1a involves phospholipase C activation and inositol trisphosphate (IP3) generation, leading to calcium release from intracellular stores a pathway distinct from the GHRH receptor, which primarily signals through cyclic AMP