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This damage occurs as high blood sugar levels promote the formation of advanced glycation end-products (AGEs), which can cause inflammation and oxidative stress, further exacerbating neuronal damage

Generally, whether the substance does not absorb radiation over 290 nm, direct photodegradation under solar radiation cannot occur, because of absorptive properties of the ozone layer (Tonnesen 2004)

Climate change adaptation as a global public good: implications for financing

In addition, orlistat's potential to cause liver damage and its association with severe liver outcomes, such as gallstone formation, obstructive jaundice, and acute liver failure, have been documented [68, 70]