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The plaque build-up tends to damage the inner lining of the blood vessels (called endothelium) throughout the body

The FDA claimed to envision such an environment when Scott Gottlieb, then the agencys commissioner, stated in 2017 that Nicotine lives at the core of both the problem and, ultimately, the solution to the question of addiction and the harm caused by combustible forms of tobacco

Jeremiah Johnson, 43, of Glasgow, Missouri, credits e-cigarettes with helping him overcome an 18-year addiction to tobacco

So, while technically true in cells in culture, in intact humans, there is no evidence that this is a concern, and nicotine is not considered a carcinogen