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Smoking Linked to Rising Cancer Rates As lung cancer cases worldwide rose rapidly by the mid-20th century, a landmark 1956 study in England surveyed the smoking habits and health outcomes of 34,400 British doctorsand linked smoking to lung cancer

We found that, due to small numbers of studies, inconsistency in the data, small effect sizes or a combination of these reasons, seven outcomes for which some previous research had found an association with smoking did notunder our meta-analytic framework and conservative approach to interpreting the datahave evidence of an association