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Researchers believe this is due to the introduction of antibiotics, immunosuppressant drugs, and an increase in the number of people who have diabetes, AIDs, and other immunosuppressive conditions

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Imperial warned that the rapid growth in black market cigarettes across Europe meant that its first-half profits this year would be down on last years

"The proposed closures reflect declining industry volumes in Europe, impacted by tough economic conditions, increasing regulation and excise and growth in illicit trade," the statement said