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ALC is essential in the metabolism of fatty acid in mitochondria, and could raise the pain threshold by enhancing the activity of cholinergic nerves [15], which is thought to be associated with the expression of GRM2 gene [16]

For hospitalization and ED visits, the IRs were 210.4 and 150.9 in GLP-1RA users, compared with 231.3 and 193 in non-users, respectively

Here, we investigated the efficacy of tirzepatide (TIR), an antidiabetic agent that improve cognitive function in diabetic rats, in alleviating cognitive impairment in DXN-treated rats

Under inflammatory stimuli (e.g., LPS), the IKK complex is activated, leading to the phosphorylation and degradation of IB, thereby releasing NF-B and promoting its nuclear translocation (Liu et al., 2017)