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Correspondingly, the AAPC for ASMRs was 4.80 (95% CI: 5.00 to 4.60) in the Republic of Korea, 4.80 (95% CI: 7.10 to 2.40) in Singapore, 4.40 (95% CI: 8.00 to 0.60) in Kuwait, and 4.20 (95% CI: 5.40 to 3.10) in Colombia
These results stand in contrast to a purely dopaminergic reward theory, leading to a better understanding of the neurobiology of nicotine motivation and possibly to improved therapeutic treatments for smoking cessation.
Even a minor error in compliance can lead to large penalties such as hefty fines, criminal charges, or a maximum of three-year prison term in some cases
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