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The first study examined dogs affected by myxomatous mitral valve disease and found that individuals living in households with smokers exhibited statistically significantly lower plasma concentrations of tetrahydrobiopterin (p=0.01) [a cofactor for endothelial-derived vasodilator nitric oxide, whose depletion is associated with oxidative stress], suggesting that passive smoke exposure may contribute to oxidative imbalance 37

The units display was only somewhat accurate (within 3 psi) and erred (pun intended) on the side of inflating to a slightly higher PSI than shown on the display

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Diarrhea Shallow breathing Slower heartbeat Low blood pressure Lethargy Weakness, sluggish reflexes, or inability to regulate muscles Seizures McLaughlin I, Dani JA, De Biasi M