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Yes, it very well could
You can read some tobacco-related adverse experience reports on the Tobacco Product Problem Reports page
The levels of Pb, As, Cd, and Cu exceeded the permissible daily average of consumption of these metals.[] Arsenic was detected in all 25 different smokeless tobacco samples analysed.[] Biomarkers of tobacco exposure Specific exposure to toxicants is demonstrated by their presence in the body fluids of exposed individuals, while elevated levels of xenobiotic detoxification products and detoxifying enzymes denote response to toxic agents in general
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