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First, federal Treasurer Joe Hockey adds profit-shifting to the Brisbane G20 agenda, his sights sharpened by media reports of Microsoft only paying 9.4 per cent tax on offshore profits, Google less at 2.6 per cent and Apple even pipping that effort at 1.9 per cent

[20] The alteration in biosynthesis of NO and its decreased activity, [21] in combination with the smoking-induced reduction in prostacyclin production [22] and the direct toxic effect of nicotine on endothelial cells that causes direct structural damage, [17] are important factors that may lead to endothelial dysfunction ( Figure 1 )

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., Fischman, M.W., Foltin, R.W., Fowler, J.S., Abumrad, N.N., Vitkun, S., Logan, J., Gatley, S.J., Pappas, N., Hitzemann, R