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If you are considering alternatives or seeking harm reduction strategies, options like nicotine replacement therapy (NRT) or FDA-authorized reduced-risk products may be more appropriate than traditional tobacco cigarettes 3

India is one of the four countries that shared more than 50% of the 6.3 million deaths and 155 million DALYs attributable to tobacco use worldwide [20]

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[29] In mucous membranes, hyperkeratosis can be defined as "an increase in the thickness of the keratin layer of the epithelium, or the presence of such a layer in a site where none would normally be expected." [22] In leukoplakia, the hyperkeratosis varies in thickness and may be either ortho- or para-keratosis, (depending upon whether cell nuclei are lost or retained in the superficial layers respectively), or a mixture of both in different areas of the lesion