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Biochim Biophys Acta 1378:F21F59 Bode AM, Dong Z (2005) Signal transduction pathways in cancer development and as targets for cancer prevention

Furthermore, nicotine and chemical constituents of both TS and e-cigs have been reported to interact with the liver cytochrome P450 (CYP-P450) enzymes and affect plasma drug levels of certain central nervous system (CNS) drugs (Zevin and Benowitz 1999

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