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Severe Risks Specific to Methamphetamine The following risks are either specific to methamphetamine or disproportionately severe compared to Adderall misuse: Methamphetamine-induced psychosis: excess dopamine in the mesolimbic system from high-dose or chronic methamphetamine use produces hallucinations, persecutory delusions, and paranoid ideation clinically resembling schizophrenia-spectrum psychosis, which can persist weeks after the last use

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