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Based on these data, the BPRF analysis suggests that the use of chewing tobacco increases the risk of esophageal cancer by at least 2% with a BPRF of 1.02 (Table 2)

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Image Credit: bildfokus.se / Shutterstock About the study In this study, researchers conducted a systematic review and meta-analysis across three scientific databases (Global Index Medicus, Web of Science, and PubMed) to analyze relationships between chewing tobacco and stroke, ischemic heart disease, and five types of cancer of the neck and head