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gnavus often coincides with impaired gut barrier function, elevated serum calprotectin, and higher lipopolysaccharide (LPS) levels, suggesting that it exacerbates disease by promoting inflammatory cytokine secretion and increasing gut permeability

To further explore whether fat-7(-) mutants are themselves resistant to MID, we mated these worms with WT (N2) males and scored their lifespan

31,32 An Anticholinergic Burden Calculator is available at no cost for use here: A small longitudinal study of 69 participants found those who took an anticholinergic medication in combination with the cholinesterase inhibitor donepezil over a two year period declined by seven points on the Mini-Mental State Examination as compared with a three point decline in those taking donepezil alone

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