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These observations indicate a deterministic shift of healthy oral microbiome during environmental stress conditions, like tobacco consumption, to a more dispersed microbial community composition in tobacco consuming individuals that is similar to the microbiome associated with OSCC buccal site ( Figure 7 )

Roosaar A, 2006 Oral mucosal lesions, tobacco use and the long-term outcome in a Swedish population

The wife who will establish the rule of allowing her husband to have the last word, will achieve for herself and her sex a great moral victory

Cravings may recur, but each craving episode is likely to last just a few seconds