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It helps confirm molecular identity, sequence integrity, impurities, and structural modifications that are essential for demonstrating biosimilarity and regulatory compliance while supporting successful biosimilar bioanalysis workflows

5.4.1 CRISPR/dCas9-based methylation manipulation Innovative studies utilizing CRISPR/dCas9-TET1 systems for targeted DNA demethylation have provided direct evidence for the causal role of DNA methylation in EED-induced reproductive dysfunction