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In 2011, the IOM issued a further report (Institute of Medicine2011) on the science needed to assess such products, which it identified as "modified-risk tobacco products" or MRTPs

[4] Research into low-nicotine cigarettes and effects on smoking frequency [edit] A recent small-scale study led by nicotine researcher Neal Benowitz found that smokers who were switched to cigarettes with tobacco that contained progressively less nicotine did not compensate by smoking more cigarettes, although a significant minority of the smokers in the research withdrew from the study citing a dislike of the taste of the reduced-nicotine cigarettes

Sometimes they are decapitated, or fleeing monsters