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So treatment recommendations need to be individually tailored

Acknowledgements We thank Professor David Nutt and Professor Stephan Ripke for their helpful comments on the manuscript

A second clinical and echocardiographic examination was performed after a total of 45 minutes from caffeine assumption in group 1, after 15 minutes from beginning of cigarette smoking in group 2, and after 45 minutes from caffeine assumption (i.e., 15 minutes from beginning of cigarette smoking) in group 3

The proportion of cancer deaths attributable to cigarette smoking varies substantially across states [but] is highest in the South, where up to 40 percent of cancer deaths in men are caused by smoking, wrote lead author and senior epidemiologist Joannie Lortet-Tieulent of the ACSs Surveillance and Health Services Research Program in Atlanta, Georgia