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"Taxes only work when they are large enough to deter you from starting smoking, or to stop people currently smoking from purchasing cigarettes." Missouri Cures, a nonprofit that promotes stem cell research and other medical advances, cites a provision of Amendment 3 that prohibits using the funds for abortion-related purposes, or for "therapies or cures using human embryonic stem cells ..." It also prohibits funding for "tobacco related research of any kind." Dueker defended the provision

Cross-border shopping, illegal markets, and consumers simply switching to non-menthol cigarettes resulted in the New England region seeing no sizable decline in aggregate smoking compared to other regions of the country following Massachusetts menthol ban