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H4K12 can loosen the connection between DNA and core histone through acetylation, and enhance the transcriptional activity of genes, thus affecting the expression of many downstream proteins

"It's all about it coming to life locally, whether it's cigarettes in Philly or ocean plastic in Rio." But he offered a reminder: These processes couldn't happen without community buy-in and those small, metal boxes

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Secondly, since the majority of participants in the GWAS of tobacco use were ancestrally Europeans, extrapolation of the results in the present study to other ethnic groups might be limited