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Therefore, either enhancing HO-1 expression or directly delivering CO ameliorated ischemia/reperfusion injury and graft rejection, alleviated chronic allograft failure, and facilitated donor-specific allograft tolerance (39, 42, 43)

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Department of Internal Medicine, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South Africa Abstract Background :Neutrophil extracellular traps (NETs) constitute a network of chromatin fibres containing histone and antimicrobial peptides that are released by activated neutrophils

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