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Graham In JAMA (Journal of the American Medical Association) 1950 (volume 143), pages 329-336 Reprinted with commentary in The Journal of NIH Research May 1982 [Curators note: One of the individuals who played a major role in proving a causal association between cigarette smoking and lung cancer was a medical student, Ernst Wynder

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Available evidence also suggests that there is a relationship between TS and myeloid leukemia, and the risk increases with increasing the duration and amount of cigarette smoking [2]