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(The presence of significant percentages of other constituents (e.g., water and flavor chemicals) will affect the boiling point.) Temperatures higher than the boiling point of an e-liquid are possible in the coil zone if the rate of e-liquid delivery to the coil does not keep pace with the heat delivery rate: the vicinity of the coil becomes dry, and the heat delivery rate surpasses the rate at which heat is carried away by evaporated liquid as latent heat

The odds ratios (ORs) for current male smokers consuming more than 30 cigarettes daily were 103.5 for SqCC and 111.3 for SCLC, indicating a steep risk gradient compared to adenocarcinoma (AdCa)

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Given that COPD diagnoses are rarely made before age 40, and consistent with national COPD cohorts, 21-23 we limited our sample to adults aged 40 years who have ever had a COPD diagnosis at Wave 5 for the cross-sectional analyses (N=1670)