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The e-cigarette group abstinence rate was 18% at 12 months, though 80% continued use of e-cigarettes, compared with a 9% abstinence rate in the NRT group and a 9% rate of continued use of NRT

While a study found that IQOS was less cytotoxic than CS to human lung epithelial cell line (A549) (9095% estimated reduction in cytotoxicity), both products yielded reduced levels of glutathione (antioxidant) and increased carbonylation of proteins (markers of chronic lung diseases) 23

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