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This can cause a buzzed or relaxed sensation, says cardiothoracic surgeon Alexandra Kharazi, MD

Around the world, tobacco kills more than 8 million people each year

And many people grasped that much earlier: The Atlantic contributor James Parton wrote back in 1868 that it does not pay to smoke. When he quit tobacco, he had fewer headaches, enjoyed exercise more, and held a better opinion of myself (though I admit that his prescribed method for kicking the habitdrinking a good stiff glass of whiskey and water instead of reaching for a pipehasnt held up very well)

Five to six capfuls in an inexperienced user can lead to deep coma (RLS 8), respiratory depression, slow heart rate with the risk of seizures and sudden death