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Though some states have made indoor vaping illegal, many smokers can inhale nicotine at all times of the day, which makes anxiety-related smoking a much bigger issue than before. Does nicotine cause anxiety

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In light of its superior safety profile, Health Canada mandated a label change in 2013 advising thorough consideration of NRT before prescribing either varenicline or bupropion to any smoker, further stating that in many cases, nicotine replacement therapy should be tried before prescribing varenicline or bupropion [9], emphasizing the need to optimize the effectiveness of this first-line medication