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10.3233/JPD-181503 75 ZhengD.LiN.HouR.ZhangX.WuL.SundquistJ.et al (2023)
According to Katrina Ubell, MD, host of the podcast Weight Loss for Busy Physicians, it can be a "godsend" or some, "but it's not meant for someone who just has those last 20 pounds to lose." And as Amy Shah, MD, points out, the drugs aren't intended for people who can lose weight by adopting healthy lifestyle and diet measures
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Preclinical studies have found that Ex-4 significantly upregulates Sirt3 expression in glioblastoma by activating the GLP-1R, which subsequently inhibits the growth, migration, invasion, and epithelial-mesenchymal transition of glioma cells [87]
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