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doi: 10.34133/research.0107 319 SchneiderTZhaoLZhuZGabrielyanGXiaoHFajardoEDet al

The nutrient displacement theory suggests that the displacement of protective anti-inflammatory lipids, such as omega-3 PUFAs (docosahexaenoic acid, EPA), contributes to increased inflammatory signaling via the disinhibition of phospholipase A2, which normally mediates the production of pro-inflammatory mediators (117)