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IGF-1 stimulates the proliferation and differentiation of satellite cells, which are responsible for repairing damaged muscle tissue after exercise or injury

Table 18: Percent Change from Baseline in BMI after 52 Weeks of IMCIVREE Treatment in Patients Aged 2 to Less Than 6 Years with Obesity due to POMC Deficiency, LEPR Deficiency, or BBS (Trial 5) Supportive of IMCIVREEs effect on weight loss, general numeric improvements in waist circumference were observed

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