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Data about tobacco smoking and alcohol consumption ( Figure 2 :++) indicated that are still the most prominent causes of cancer worldwide and are considered significant for OCSCC occurrence, and, as evidenced by studies published in the recent years, the comparison of the proportion of individuals reporting tobacco and alcohol consumption showed that these habits were more prevalent in the older group (48.4% and 45.8%, respectively) than in the younger group (39.5% and 30.9%, respectively)

Bane, Lorenzo Benet (1995) "The Lives of Danielle Steel: The Unauthorized Biography of America's #1 Best-Selling Author" ISBN 0-312-95575-8 p

Congress banned flavored cigarettes as part of the 2009 law giving the FDA authority to regulate tobacco products, but a loophole negotiated by industry lobbyists exempted menthol

Smoking and immune system Smoking is detrimental to the immune system and reduces the bodys ability to fight off diseases and infections