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While in this short-term study there was no association between exclusive e-cigarette use and cardiovascular events, there was an association with incident COPD and possibly hypertension that will need to be closely watched over longer term follow-up. The study was partially funded by grants from the National Heart, Lung, and Blood Institute of the National Institutes of Health, and the U.S

E-cigarettes were charged the day before the experiment and swapped after 15 puffs (one series of aerosol generation) if the level of battery capacity dropped below 50%

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