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Further, hepatocyte proliferation parameters should be corroborated other parameters such as regression of injury, final recovery, and survival to demonstrate clinical significance of the interventions on final outcome

Mice in both groups were fasted for 12 hours at the ages of 12, 16, and 20 weeks, and were anesthetized with sevoflurane (Wako, Osaka, Japan), followed by blood and tissue collection at the end of the experiment