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Brunner, A

These alternatives can help accelerate weight loss by boosting GLP-1 levels, improving insulin sensitivity, and enhancing insulin release, all contributing to effective weight reduction without significant side effects

WC showed the highest measures in the liraglutide and the least values in the control group (p = 0.011)

In vitro endocrine differentiation of these lines confirmed the absence of RFX6 expression in RFX6 / lines and significantly reduced RFX6 expression in the RFX6 + / line, confirming haploinsufficiency due to the heterozygous variant