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The National Institutes of Health (NIH) says there are at least 250 harmful chemicals in tobacco smoke, and at least 69 are carcinogens, such as arsenic, benzene and formaldehyde

For users of tobacco, wood stoves, or other consistent sources of smoke (high exposure, long term, indoor source): If smoke is produced inside the home, the first line of defense is always ventilation with outdoor air by opening all possible windows or doors and activating any fans attached to vents

The problem with the larger devices is that they will take up more of your time and use a lot of e liquid

But these are typically labeled as such, so if you're not into tobacco, they're easy to avoid