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but amongst the Bees, the males of Apis mellifica , Anthidium manicatum and Anthophora acervorum , and amongst the Fossores, the males of the Methoca ichneumonides , are larger than the females

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So Selye began to suggest that subjecting an animal to prolonged stress led to tissue changes and physiological changes with the release of certain hormones, that would then cause disease and ultimately the death of the animal." And so the idea of stress and it's potential costs to the body was born