This approach transcends the conventional focus solely on the antifungal properties of nanomaterials, offering a fresh perspective that aligns with cellular dynamics
The binding of the RGD motifs to the V integrins expressed in tumor endothelial cells induces the protease-mediated cleavage of the iRGD peptide, producing two peptides, namely, CRGDR/K and GPDC
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179,180 Nonetheless, through the integration of multi-omics analysis and validation both in vitro and in vivo in NSCLC, a recent study disclosed that intracellular lactate drives extracellular lipolysis and FFA release via non-histone lactylation of apolipoprotein C-II (APOC2), bringing about immunotherapy resistance